Physicochemical properties of calcium phosphate cement incorporated with anti-tumor drugs
- VernacularTitle:抗肿瘤药物复合磷酸钙骨水泥的理化性质研究
- Author:
Huajiang CHEN
;
Lianshun JIA
;
Jianru XIAO
;
Xinghai YANG
- Publication Type:Journal Article
- Keywords:
bone cements;
calcium phosphates;
antineoplastic agents;
physicochemical properties
- From:
Academic Journal of Second Military Medical University
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the influence of anti-tumor drug incorporation on the physicochemical properties of calcium phosphate cement(CPC).Methods: Methotrexate(MTX),epirubicin(EPI),hydroxy camptothecin(OH-CPT),and arsenic trioxide(As_2O_3) were incorporated,each in a proportion of 2%,5%,and 8%,into the powder-phase CPC.Untreated CPC was taken as control.The setting time,compression strength,and the microstructure of the resultant products were evaluated and tested.Results: Compared with control group,the setting time was significantly prolonged when 2% EPI was incorporated into CPC(P
