Significance of p16 expression in malignant mesothelioma
- VernacularTitle:p16基因在恶性间皮瘤组织中的表达及其意义
- Author:
Guo YU
;
Guanghai DAI
;
Gang REN
- Publication Type:Journal Article
- Keywords:
malignant mesothelioma;
genes,p16;
immunohistochemistry;
histomorphology
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of p16 gene in malignant mesothelioma,and its relationship with histological types,clinical stages and prognosis.Methods Immunohistochemical staining was used to detect the expression of p16 gene in the specimens of 80 cases of malignant mesothelioma.Results The positive expression of p16 gene was found in 35% malignant mesothelioma specimens,and negative in 65%(P