Effect of ultraviolet C irradiation on the expression of basic fibroblast growth factor in gunshot wounds in limbs
- VernacularTitle:四肢火器伤受紫外线照射后碱性成纤维细胞生长因子的表达
- Author:
Wei SUO
;
Jie HU
;
Ming FANG
- Publication Type:Journal Article
- Keywords:
ultraviolet C;
gunshot wounds;
fibroblast growth factor
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of different irradiation doses of ultraviolet C ray(UVC)on the expression of basic fibroblast growth factor(bFGF)in granulation tissue of gunshot wound in rabbit limbs.Methods After giving 30mJ/cm2 or 60mJ/cm2 UVC to the gunshot wound of soft tissue of limbs,the expression of bFGF was observed both at the mRNA level and the protein level by the methods of in situ hybridization and immunohistochemistry,respectively.Results On the 7th day after UVC irradiation,the expression of bFGF in UVC-treated groups was significantly higher than that in control group(P