Detection of three kinds of cytokines in patients with viral myocarditis.
- VernacularTitle:病毒性心肌炎肿瘤坏死因子-?白介素-2及白介素-1?的检测及其意义
- Author:
Bo HU
;
Jue XU
;
Guoqiang HONG
- Publication Type:Journal Article
- Keywords:
Viral myocarditis;
Tumor necrosis factor;
Interleukin-2;
Interleukin-1?
- From:
Chinese Journal of Practical Internal Medicine
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of TNF-?,IL-2 and IL-1? level in serum of patients with viral myocarditis and its clinical meaning.Methods The level of serum TNF-?,IL-2 and IL-1? in 45 cases of viral myocarditis was detected by ELISA,and the data were compared with control group.Results Serum TNF-?,IL-2 and IL-1? levels in viral myocarditis patients were significantly higher than control group and related to severity of the disease.Conclusion It suggests that immune dysfunction exists in patients with viral myocarditis.Higher level of TNF-?,IL-2 and IL-1? may be associated with development of the viral myocarditis,and it can be a new indicator for viral myocarditis.