Relationship of Chemokine Interleukin-8 mRNA Expression and Tumor Infiltrating Lymphocyte and Neutrophil in Gastric Carcinoma.
- VernacularTitle:趋化因子IL-8与胃癌组织中浸润炎性细胞相关性分析
- Author:
Zhong JIA
;
Guanhhai HE
;
Guanghua FENG
- Publication Type:Journal Article
- Keywords:
Interleukin-8;
Gastric cancer;
Tumor infiltrating lymphocyte;
Myeloperoxidase;
Neutrophil
- From:
Journal of Medical Research
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of chemokine interleukin-8(IL-8) and tumor infiltrating lymphocyte.neutrophil in gastric cancer.Study the effect of chemokine IL-8 on local region immunocompetence and the mechanism of IL-8 in gastric cancer. Methods The distribution and quantitation of the subpopulations of tumor infiltrating lymphocyte including T_3、T_4、T_8 and neutrophil were studied with SABC immunhistochemistry and myeloperoxidase (MPO) kits respectively. Results Interleukin-8 and T_4/T_8 has a negative correlations (?=-0.52,P
