Investigation on the Express of P15 and the P16 protein in the Brain Gliomas.
- VernacularTitle:P15及P16蛋白在脑胶质瘤中表达的研究
- Author:
Guihua XING
;
Xiaojie ZHANG
;
Wei RONG
- Publication Type:Journal Article
- Keywords:
Brain gliomas;
p16 p15 gene;
Immunohistochemistry
- From:
Journal of Medical Research
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate cancer suppressor Genes p16, p15 in the brain gliomas expression and its relations with the gliomas pathology graduation and the malignant degree.Methods P16 and P15 protein expression level in human brain gliomas from 63 surgery specimens were assayed by immunobistochemical S-P method.Results P16, the P15 protein expression rate the brain gliomas pathology graduation assumes the inverse correlation with, also compared with the high malignant group the low malignant group (Ⅰ~Ⅱ level) (Ⅲ~Ⅳ level) has the remarkable difference (P
