Research progress of T-type calcium channels and the related drugs
- VernacularTitle:T型钙通道及其作用药物研究进展
- Author:
Zhiguo ZHANG
;
Qingzhu ZHANG
- Publication Type:Journal Article
- Keywords:
T-type calcium channel;
molecular structure;
physiological function;
drug effects
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
T-type calcium channels present in cardiovascular, neuronal and endocrine systems, and they are now receiving attention as novel therapeutic targets. It plays important roles in multiple cellular functions and genes those encode the T-type calcium channels have been recently reported. Many drugs and compounds non-specifically block T-type calcium channels. We review circumstances of the research of T- type calcium channels in the molecular structure, distribution, function, regulation and the related drugs.