Relationship between analgesia and hypnosis of isoflurane and glycine site of NMDA receptor
- VernacularTitle:异氟烷催眠、镇痛作用与NMDA受体甘氨酸位点的关系
- Author:
Ruiming WANG
;
Cai FANG
;
Huiping LI
;
Tijun DAI
- Publication Type:Journal Article
- Keywords:
isoflurane;
hypnosis;
analgesia;
glycine site of NMDA receptor;
Fos-protein
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Intrathecal administration of D-serine (0.025, 0.05, 0.1 ng), antagonized analgesia induced by isoflurane in tail-immersiontest and the early phase of formalin test (P0.05). Intrathecal administration of D-serine (0.05 ng) antagonized and the isoflurane′s suppression to the expression of Fos-protein in the spinal cord in mice(P
