Analysis on the immunoregulation of combined therapy of ulinastatin and thymosin ?_1 in the treatment of sepsis
- VernacularTitle:乌司他丁联合胸腺肽?_1对脓毒症患者免疫调理的合理性分析
- Author:
Lei SU
;
Dianyuan ZHOU
;
Youqing TANG
- Publication Type:Journal Article
- Keywords:
sepsis;
multiple organ failure;
immuno-recuperative function
- From:
Medical Journal of Chinese People's Liberation Army
1983;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the influences of combined therapy of ulinastatin and thymosin ?1 on the immune state in the treatment of sepsis and multiple organ failure(MODS),and to evaluate the therapeutic rationality.Methods 46 patients with sepsis and 18 patients with MODS were randomly divided into two groups.The patients in control group were treated with classical SSC therapy,those in treatment group were treated with the combined ulinastatin and thymosin ?1 therapy.The contents of IL-6 and IL-10 were detected with ELISA at the beginning of and after the treatment.Results After treatment,the concentrations of IL-6 and IL-10 declined significantly in treatment group,while no apparent changes were observed in the control group.There existed a significant difference between the two groups(P
