Expression of human telomerase reverse transcriptase and proliferating cell nuclear antigen in pleural and peritoneal effusion
- VernacularTitle:hTERT和PCNA在良恶性胸腹水细胞中的表达及临床意义
- Author:
Liying WU
;
Bangrong LIU
;
Jun LU
;
Mingde LING
;
Jie CHEN
;
Peng LI
- Publication Type:Journal Article
- Keywords:
human telomerase reverse transcriptase;
proliferating cell nuclear antigen;
serous effusion
- From:Journal of Third Military Medical University
1984;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnostic value of human telomerase reverse transcriptase (hTERT) and proliferating cell nuclear antigen (PCNA) in pleural and peritoneal effusion. Methods The expressions of hTERT and PCNA were detected by immunocytochemistry in 46 malignant and 21 benign serous specimens. Results hTERT and PCNA were detected respectively in 39 and 29 of 46 malignant specimens, but no expressions in reactive mesothelial cells in all serous specimens. hTERT correlated with PCNA (r=0.30, P
