Detection of HBV cccDNA in Peripheral Blood Lymphocyte.
- VernacularTitle:外周血淋巴细胞中乙肝病毒cccDNA检测研究
- Author:
Dai XU
;
Xiaoxing WU
;
Jing WU
- Publication Type:Journal Article
- Keywords:
Peripheral blood lymphocyte(PBL);
HBV cccDNA
- From:
Journal of Medical Research
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Assaying HBV cccDNA in periphral blood lymphocyte and discuss its clinical significance.Methods Using lymphocyte isolating solution to isolate lymphocytes in the peripheral blood, and quantitative florescent realtime PCR was used to detect HBV cccDNA.Results 29 cases of 36 CAH patients was detected positive(80.56%),32 cases of 61 CPH patients was detected positive(52.46%) and 1 case of 59 ASC was detected positive(0.02%) respectively.All 47 healthy people specimen was found negative by the method.CAH group,CPH group and ASC & negative control group show significance statistically(P
