Effect of Different Starting Dose Methylprednisolone on Acute Exacerbations of Chronic Obstructive Pulmonary Disease.
- VernacularTitle:不同初始剂量甲泼尼龙对慢性阻塞性肺疾病急性发作期治疗的影响
- Author:
Baoxian HUANG
;
Baiqiang ZHONG
;
An SHENG
- Publication Type:Journal Article
- Keywords:
Methylprednisolone;
Chronic obstructive;
Pulmonary disease;
Corticosteroid
- From:
Journal of Medical Research
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate effects of different starting dose methylprednisolone on acute exacerbations of chronic obstructive pulmonary disease(AECOPD).Methods 40 patients with AECOPD were allocated two groups in random,including group A(n=20,120mg methylprednisolone)and groups B(n=20,80mg methylprednisolone),with duration of treatment was 7 days respectively.Clinical sign and symptom,dyspnea score and arterial blood gases were measured and observed at 0-hour,72-hour,day 7.Results The group A was surperior to the group B in clinical efficacy.The differences of dyspnea score and arterial blood gases at 72-hour are significant between the two groups(P
