The Morphometric Study of Bony Tissue in the Rat Experiment of Bone Union Enhanced by the Red Rice
- VernacularTitle:红曲促进实验大鼠骨折愈合的骨组织形态计量学观察
- Author:
Chunlei WU
;
Jianlin HUANG
;
Weijia WANG
- Publication Type:Journal Article
- Keywords:
fracture;
traditional Chinese medicine;
red rice;
pharmacodynamics;
the morphometry of the bone tissue;
animal;
rats
- From:
Journal of Zhejiang Chinese Medical University
2007;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To investigate the curative effect of the red rice in treating the experimental fractures in the rats.[Methods] 64 Wistar rats suffered with single fracture in the forearm were randomized into two groups,one red rice group and the other normal saline control group.On the twenty-first day and 42 day after operation,the qualitation and morphometric observation of the bone tissue were performed.[Results] After the treatment of the red rice,the bony union of the fractured bone in the rats was obviously accelerated.The morphometric index of the bony tissue was higher than the control group with the statistical significance.The remodeling of the bony callus,the emergence of the lamellar bone and recanalization of the medullary cavity could all be enhanced by the use of the red rice.The mineralized bony callus area,the osteoblast index and the matrical calcification were obviously higher than those of the control group.[Conclusions] The growth of bony callus,the index of the osteoblast,the metrical calcification and the remodeling of the bony callus could all be enhanced by the red rice and therefore the bone union could be accelerated.