Transgenic mouse models of inhibition of tumor angiogenesis
- VernacularTitle:在肿瘤研究中转基因小鼠模型的研究进展
- Author:
Hongying LIN
;
Runting YIN
;
Tao XI
;
Hanmei XU
- Publication Type:Journal Article
- Keywords:
transgenic mouse model;
tumor;
angiogenesis
- From:
Chinese Pharmacological Bulletin
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
With the development of recombinant DNA technology, genetically altered mouse models for human cancers are critical to the investigation and characterization of oncogene and tumor suppressor gene expression and function and the associated cancer phenotype. Recently, the inhibition of tumor angiogenesis becomes a new “hot spot” in cancer researches. And the genes involved in the regulation of tumor angiogenesis play an increasingly important role in the field of tumor researches. This review is about the progress of the research in transgenic tumor models and focuses on genes regulating tumor angiogenesis associated with transgenic mice model.
