The relation of hypoxia-inducible factor with inflammation and tumor
- VernacularTitle:缺氧诱导因子与炎症及肿瘤的关系
- Author:
Yun ZHANG
;
Chonggao ZHANG
;
Huaxi XU
- Publication Type:Journal Article
- Keywords:
hypoxia-inducible factor;
inflammation;
malignant tumors
- From:
Chinese Pharmacological Bulletin
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Regional microenviroment hypoxia is a common feature in inflammation and malignancy. Cells are able to trigger an adaptive response to hypoxia conditions that result in hypoxia-inducible factor(HIF)overexpression. Based on a brief description of the structure and functions of HIF, this article discusses the relationship between inflammation, tumor and HIF.
