DNA topoisomerase and antitumor
- VernacularTitle:DNA拓扑异构酶与抗肿瘤
- Author:
Xiaomei MO
;
Jing LI
;
Meiyu GENG
- Publication Type:Journal Article
- Keywords:
DNA topoisomerase;
antitumor;
atMDR
- From:
Chinese Pharmacological Bulletin
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
DNA topoisomerase is a basic enzyme in eucaryon and prokaryotic cells, which distributes in cell nucleus generally. DNA topoisomerase plays important roles in the process of duplication, transcription, translation, recombination and chromosome monomer isolation to control, keep and modify the DNA topology. It is reported that DNA topoisomerase has a high expression level, which related with the mechanism of many antitumor drugs.
