Effects of hypoxia on morphology and survival of rat Sertoli cells
- VernacularTitle:低氧对大鼠睾丸支持细胞形态结构与存活率的影响
- Author:
Weihong LU
;
Huaijun TIAN
- Publication Type:Journal Article
- Keywords:
hypoxia;
Sertoli cell;
skeleton
- From:Journal of Third Military Medical University
1984;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of hypoxia on cultured rat Sertoli cells in vitro.Methods In a Sertoli-germ cells co-culture system,the effect of hypoxia on the morphological characteristics of Sertoli cells were observed,including the number of Sertoli cells,the cytoskeleton changes after Coomassie brilliant blue staining and the detachment of germ cells.Results The loosing and retracting of cytoskeleton in Sertoli cells was found.Both survival rate of Sertoli cells and detachment of germ cells showed time-response relation.Conclusion Hypoxia damages Sertoli cells.
