Study on Prognosis of Atypical Kawasaski Disease Treated with Intravenous Gamma Globulin(IVGG)after Abatement of Fever
- VernacularTitle:不典型川崎病患儿热退后应用丙种球蛋白治疗剂量及预后关系
- Author:
Liqun JIANG
- Publication Type:Journal Article
- Keywords:
Atypical Kawasaski disease;
Intravenous gamma globulin(IVGG);
Children;
Coronary artery
- From:
Journal of Medical Research
2006;0(12):-
- CountryChina
- Language:Chinese
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Abstract:
Objective To study the dose of IVGG in treating atypical Kawasaki disease(KD) at defervescence and the necessity.Methods Clinical data of 54 cases of atypical Kawasaski disease without coronary artery lesion (CAL) but with the abatement of fever in 10 days were retrospectively analyzed. They were divided into there groups according to IVGG dosage ;group A (1g/kg IVGG n=11 ),group B(2g/kg n=24 ) and group C (blank n=19 ) .CAL was observed to at 14~21 days and 0.5year. Results Compared with group A and B, The rate of CAL was significantly higher (P0.05) . Conclusions In order to prevent CAL ,atypical Kawasaki disease(KD) children with confirmed diagnosis in 10 days should all be treated with IVGG whether with abatement of fever or not .The dose of 1g/kg IVGG would have satisfactory effects on atypical KD children at defervescence.
