EFFECTS OF TOTAL FLAVONOIDS EXTRACT OF TARTARY BUCKWHEAT GERM ON SERUM LIPIDS AND ANTIOXIDATION IN HYPERCHOLESTEROLEMIC RATS
- VernacularTitle:苦荞麦总黄酮对高脂血大鼠血脂和抗氧化作用的影响
- Author:
Min WANG
;
Yimin WEI
;
Jinming GAO
- Publication Type:Journal Article
- Keywords:
tartary buckwheat;
flavonoids;
serum lipids;
hepatic lipids;
antioxidant enzyme
- From:
Acta Nutrimenta Sinica
2004;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effects of the total flavonoids of tartary buckwheat germ (TFTBG) on serum lipid and antioxidation in hypercholesterolemic rats. Method: According to body weight,60 Wistar rats were divided randomly into 6 groups: normal control group (NC), high-fat control group (HFC), Jiaogulan positive control group (JPC, Gynostemma pantaphyllum total glucoside tablet 0.032g/kg bw),TFTBG 1.0,0.5and TFTBG 0.2 g/kg bw (HD,MD,LD) group. Except NC group, all other groups were fed high-fat diet for hyperlipidemia model. NC group and HFC group were given distilled water 10 ml/kg bw. Water and TFTBG were given by gavage once a day for 6 w respectively. Serum TG, TC HDL-C, LDL-C, apoA1, apoB, SOD, GSH-Px and MDA were determined. Results: Compared with HFC group, serum TG ,TC were lowered significantly(P
