Design and optimization of pulse sequence for quantitative measurement of ?-aminobutyric acid concentration using MR spectroscopy
- VernacularTitle:基于MRS定量检测?-氨基丁酸浓度的序列设计及优化
- Author:
Yaowen CHEN
;
Bing LIANG
;
Zhiwei SHEN
- Publication Type:Journal Article
- Keywords:
magnetic resonance spectroscopy;
quantitative measurement;
gamma-aminobutyric acid;
spectral editing;
pulse sequence;
optimization
- From:
International Journal of Biomedical Engineering
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To design and optimize the MRS pulse sequence which used to measure gamma-aminobutyric acid(GABA) in vivo. Methods In-depth research for the MRS sequence was carried out and a theoretical analysis and simulation by software using product-operator algebra for the design and optimization of pulse sequence was discussed. Results Through the simulation of MRUI software, Cr signal at ?3.0 was seen to be suppressed and the weak GABA signal was displayed clearly. Conclusion The sequence was designed and optimized. Method to increase the efficiency and the stability of the measurement was studied. Our research gives theoretical preparation for the coming programming work.
