Expression and clinical significance of CDx2 and Hep in gastric carcinoma
- VernacularTitle:CDx2和Hep在胃癌组织中的表达及临床意义
- Author:
Xinmu ZHOU
;
Shaojie XU
;
Yiling ZHU
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
CDx2;
Hep
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression and clinical significance of CDx2 and hepatocyte antigen(Hep) in gastric carcinoma.Methods The expression of CDx2 and Hep in 9 cases of nomal gastric mucosa,15 cases of small intestinal mucosa,8 cases of colon mucosa,15 cases of intestinal metaplasia of the stomach and 130 cases of gastric carcinoma were detected with immuohistochemical EnVisionTM Systems measures.Results The positive rates of CDx2 expressed in the nomal gastric mucosa were 0,small intestinal mucosa 80%(12/15),colon mucosa 87.5%(7/8),intestinal metaplasia of the stomach 86.7%(13/15),gastric carcinoma 37.7%(49/130);The positive rate of Hep was 11.1%(1/9),86.7%(13/15),12.5%(1/8),100%(15/15),55.4%(72/130) respectively.There was much higher positive expression of CDx2 in intestinal-type carcinoma than in diffuse-type gastric carcinoma(P
