Thyroperoxidase expression in fine needle aspirated thyroid tumor cells and it clinical relevance
- VernacularTitle:甲状腺过氧化物酶在细针抽吸甲状腺肿瘤细胞中的表达及意义
- Author:
Wei QU
;
Ling JIANG
;
Yanmei ZHANG
;
Zhimi LIU
- Publication Type:Journal Article
- Keywords:
thyroid neoplasms;
iodide peroxidase;
immunohistochemistry;
biopsy,fine-needle
- From:
Academic Journal of Second Military Medical University
1999;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe thyroperoxidase (TPO) expression in fine needle aspirated thyroid tumor cells and to assess the value of TPO immunostaining in differential diagnosis of benign and malignant thyroid tumors. Methods: Fine needle aspiration (FNA) samples and frozen tissue sections of 71 surgically resected thyroid tumor specimens were immunostained by with hTPO MoAb47. The staining results were considered positive if 80% or more thyroid cells were positively stained. Results: TPO expression levels in FNA samples and frozen tissue sections of malignant tumors were lower than those of benign tumors (P
