Long-term effects of neonatal recurrent seizures on ?-aminobutyric acid A receptor ?1 and ?2 subunit expressions in the rat brain
- VernacularTitle:新生大鼠反复惊厥对脑内?-氨基丁酸A受体?1和?2亚单位表达的长期影响
- Author:
Tao BO
- Publication Type:Journal Article
- Keywords:
Convulsions;
Receptors,GABA-A;
Animals,newborn;
Rats
- From:
Journal of Peking University(Health Sciences)
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).The AOD of ?2 subunit protein immunoreactivity in the frontal lobe and CA4 region decreased significantly in the seizure group than those in the control group(P0.05),but the expressions of ?1 subunits mRNA in the hippocampus and ?2 subunit mRNA in the cerebral cortex in the seizure group decreased significantly as compared with those in the control group(P
