Hyperuricemia and Ischemic Stroke
- VernacularTitle:高尿酸血症与缺血性卒中
- Author:
Lijie CHEN
;
Heyong LI
- Publication Type:Journal Article
- Keywords:
hyperuricemia;
ischemic stroke
- From:
International Journal of Cerebrovascular Diseases
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Epidemiological studies have suggested that the increase of uric acid level has a direct correlation with the risk of ischemic stroke. However,the significance of this correlation remains controversy. Most findings have suggested that hyperuricemia is a risk factor for stroke and poor outcome after stroke.Very few studies have suggested that hyperuricemia has protective effect on acute ischemic stroke.Although the effect of hyperuricemia on pathophysiological mechanisms of stroke remains uncertain, the interventional strategy by lowering the levels of blood uric acid for preventing ischemic stroke is worth to be considered. This article mainly reviews the recent clinical trials data and related mechanisms.
