Expression of leukocyte adhesion molecules at different stage in acute lung injury
- VernacularTitle:急性肺损伤不同时期白细胞粘附分子的表达及其意义
- Author:
Xigang MA
;
Zhenxiang ZHANG
;
Yongjian XU
- Publication Type:Journal Article
- Keywords:
Leukocyte;
Adhesion molecule;
Acute lung injury;
Acute respiratory distress syndrome
- From:
Chinese Journal of Practical Internal Medicine
2006;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the leukocyte adhesion molecules in the pathogrnesis of ALI and ARDS.Methods The positive expression rates of CD11a、CD11b and CD18 in peripheral blood were quantitatively analyzed by flow cytometry using monoclonal antibodies in 26 cases of ALI,18cases of ARDS and 15 healthy controls.Results The expression rates of CD11a、CD11b and CD18 in polymorphonuclear neutrophils and monocytes from the ALI group and ARDS group were much higher than those in the control group(P