Quantitative analysis of osteopontin expression in oral squamous cell carcinoma tissues and its clinical significance
- VernacularTitle:骨桥蛋白在口腔鳞状细胞癌中的定量表达及临床意义
- Author:
Lei JIANG
;
Xiaozhong JIANG
- Publication Type:Journal Article
- Keywords:
osteopontin;
mouth neoplasms;
carcinoma,squamous cell;
immunohistochemistry
- From:
Academic Journal of Second Military Medical University
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To quantitative analyze the expression of osteopontin(OPN) in oral squamous cell carcinoma(OSCC) tissues and its clinical significance.Methods: OPN expression was examined in 59 OSCC(with different clinical and pathological characteristics) and 12 normal oral mucosa(NOM) samples by using immunohistochemical method.The staining results were quantitatively studied by image analyzer.Results: OPN expression was much higher in OSCC sample than that in NOM sample(P