Effect of preoperative administration of Dextromethorphan on cough reflex during tracheal extubation
- VernacularTitle:术前肌注右美沙芬对全麻术后拔管时呛咳反应的影响
- Author:
Xiaoguang CHEN
;
Jie BAI
;
Xuefeng SUN
;
Yingmin ZHANG
- Publication Type:Journal Article
- Keywords:
Dextromethorphan;
OSAS;
cough reflex
- From:Journal of Third Military Medical University
2003;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of preoperative administration of Dextromethorphan (DM) on cough reflex of patients during tracheal extubation under general anesthesia after obstructive sleep apnea syndrome (OSAS) operation. Methods Forty ASA Ⅰ-Ⅱ adult patients scheduled for uvulopalatopharyngoplasty (UPPP) under general anesthesia were randomly divided into control group and DM group (n=20 in each group). Patients in DM group received 0.3 mg/kg DM and control group took 5 ml normal saline preoperatively. Cough reflex of patients and adverse effects were recorded during tracheal extubation. Results Cough reflex during tracheal extubation was remarkably suppressed in DM group as compared with control group (P
