Ten cases of pheochromocytoma with special clinical manifestations at onset and a review of the literature.
- VernacularTitle:以特殊临床表现为首发症状的10例嗜铬细胞瘤临床诊治分析
- Author:
Hui GUO
;
Bingyin SHI
;
Hui HE
- Publication Type:Journal Article
- Keywords:
Pheochromocytoma;
Acute coronary syndrome;
Diabetes;
Abdominal pain
- From:
Chinese Journal of Practical Internal Medicine
2006;0(22):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the ten cases of pheochromocytoma with special clinical manifestations at onset so as to improve the level of diagnosis and treatment for pheochromocytoma.Methods Clinical data of 10 pathologically diagnosed pheochromocytoma patients after operation with special clinical manifestations at onset were analyzed.The onsets of their illness were respectively presented as acute coronary syndromes,diabetes or abdominal pain.We retrospectively summarized the clinical manifestations,the biochemical characters,the treatment,and the outcomes of these 10 cases.Results The 24-hour urinary vanillylmandelic acid(VMA)87.6~175.5 ?mol,catecholamine(CA)611.1~5 421.0 nmol,epinephrine(E)168.2~2 402.0 nmol and norepinephrine(NE)422.9~3 019.0 nmol were all elevated in the 10 patients before operation.And B mode ultrasonography or CT showed positive findings in adrenal.Ten patients were all pathologically diagnosed as with pheochromocytoma after operation.The angina pectoris attacks disappeared after operation in the 2 cases with acute coronary syndromes,while in 4 cases with diabetes,their blood glucose rebound to normal range gradually after operation without any treatment,and for the other 4 cases their upper abdominal pain also disappeared after operation.Conclusion For those pheochromocytoma patients with atypical clinical manifestations,the key points for the diagnosis are based on biochemical detections and imageological findings.
