Changes in nitriergic nerves and interstitial cell of Cajal in intestinal myenteric plexus of scalded rat during early post-burn stage
- VernacularTitle:烧伤早期大鼠回肠肌间神经丛内氮能神经和Cajal间质细胞的变化
- Author:
Xu QIAN
;
Chen LIN
;
Qichuan ZHUGE
- Publication Type:Journal Article
- Keywords:
burns;
nitriergic neurons;
myenteric plexus;
interstitial cell of Cajal
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes in nitriergic nerves and interstitial cell of Cajal (ICC) in intestinal myenteric plexus of scalded rats during early post-burn stage. Methods 20 rats were randomly divided into scald group (n=10) and control group (n=10). A rat model of 30% TBSA with II degree scald was reproduced in the scald group. The rate of enteric transit was measured, and the histological changes in nitriergic nerves in intestinal myenteric plexus of scalded rat were observed as well. The densities of neurons and ganglions with positive nitric oxide synthetase (NOS) as well as ICC in duodenal myenteric plexus were assessed for both groups. Results In the rats in scalded group, the rate of enteric transit was prolonged, and the number of nitriergic nerves and ICC in myenteric plexus of rat duodenum were significantly decreased (P
