The effect of combination of D-methionine and docetaxel on gastric cancer cells
- VernacularTitle:右旋甲硫氨酸与紫杉醇联合应用治疗胃癌
- Author:
Jihong LIU
;
Weixin CAO
;
Yubao JI
;
Bingya LIU
;
Zhenggang ZHU
;
Yanzhe LIN
- Publication Type:Journal Article
- Keywords:
Methionine;
Gastric cancer;
Docetaxel
- From:
Parenteral & Enteral Nutrition
2004;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of combination of D-methionine and docetaxel on gastric cancer cells. Methods:First, seven gastric cancer cell lines were cultured with three different kinds of media (D-Met, L-Met and Met~ - ) for five days, and cell cycle was detected by flow cytometry. Second, gastric cancer cells were respectively cultured in L-Met, D-Met, and Met~ - media for 96 h, then docetaxel was added into 3 media. After 24 h, proliferation was measured by MTT method. Results:All gastric cancer cell lines were arrested in G_ 2 /M phase (P
