Change of intestinal permeability and its relationship with serum proteins in patients with pancreatic cancer
- VernacularTitle:胰腺癌病人肠道通透性改变及其与血清蛋白关系的临床研究
- Author:
Zhufu QUAN
;
Jun LI
;
Jieshou LI
- Publication Type:Journal Article
- Keywords:
Pancreatic cancer;
Intestinal permeability;
Malnutrition;
Tumor necrosis factor
- From:
Parenteral & Enteral Nutrition
2004;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:The study was designed to observe the change of intestinal permeability and its relationship with serum proteins in patient with pancreatic cancer. Methods: A prospective and controlled trial was taken. 15 patients with pancreatic cancer were chosen as experimental group. 15 healthy volunteers were as control group. Urine lactulose/mannito(L/M) ratio, serum concentration of TNF-? and serum levels of albumin(ALB), transferritin (TF) and prealbumin (PA) were measured. Results: The urine L/M ratio was significantly increased in experimental group compared with control group(0.331 vs 0.129, P