The neoplastic action mechonism of somatostatin and its application in pancreatic cancer
- VernacularTitle:生长抑素抗肿瘤机制及其对胰腺癌的治疗展望
- Author:
Changsheng HE
;
Zhufu QUAN
- Publication Type:Journal Article
- Keywords:
Somatostatin;
Somatostatin receptor;
Pancreatic cancer
- From:
Parenteral & Enteral Nutrition
2004;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
s: Pancreatic cancer remains a major unsolved health problem.Over the past decade,antiproliferative effects of somatostatin and analogs have been reported in many somatostatin receptor-positive normal and tumor cell types.Somatostatin and analogs act through five somatostatin receptors(SSTR1-5)which are variably expressed in normal and tumor cells.The present review focuses on recent advances in biological mechanisms involved in the antineoplastic activity of somatostatin and analogs.
