Development in research of polypeptides as components of nonviral gene delivery vectors
- VernacularTitle:多肽作为非病毒转基因载体组件的研究进展
- Author:
Da LI
;
Qingqing WANG
;
Hai YU
- Publication Type:Journal Article
- Keywords:
polypeptides;
nonviral vectors;
gene delivery
- From:
International Journal of Biomedical Engineering
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
In the field of gene delivery, nonviral vectors are getting more attention due to the advantages which do not belong to viral vectors. But kinds of polypeptides are important to construct ideal nonviral vectors. The paper reviews the development in the research of polypeptides as components of nonviral vectors like as the backbone, the targeting moiety, the endosome membrane destabilizing agents and the nuclear localizing signals.