Progress of electroporation in improving the efficacy of DNA vaccine
- VernacularTitle:电穿孔增强核酸疫苗免疫反应的研究进展
- Author:
Qibin HE
;
Yiping XING
- Publication Type:Journal Article
- Keywords:
DNA vaccine;
electroporation;
immune responses
- From:
International Journal of Biomedical Engineering
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
DNA vaccine plays an important role in the treatment of cancer, infectious disease and self-immune disease. Further enhancement of immune responses to DNA vaccines is one of the hot spots in the vaccine development. Among the research combining the electroporation with DNA vaccination improves plasmid gene expression in vivo and significantly enhances the immune responses. This review gives an overview of the application, effectiveness and prospect of electroporation in improving the efficacy of DNA vaccine.