Effect of endoscopic sinus surgery on 50 cases of chronic sinusitis with asthmatic
- VernacularTitle:鼻窦内镜术治疗慢性鼻窦炎合并支气管哮喘50例疗效分析
- Author:
Huaqing LI
- Publication Type:Journal Article
- Keywords:
Asthma;
Sinusitis;
Endoscopic
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of endoscopic sinus surgery(ESS) in chronic sinusitis and polyps with asthma.Methods 100 patients were divided into two groups.All patients in A group with chronic sinusitis and polyps with asthma and those in B group with chronic sinusitis and polyps were treated by ESS.The contents of interleukin-4(IL-4),interferon-?(IFN-?),soluble interleukin 2-receptor(sIL2-R) and soluble CD23(sCD23) levels were determined after treatment and before treatment by enzyme-linked immunosorbent assay(ELISA).Results The contents of IL-4,sCD23 and sIL-2R in A group before treatment were (93?47)ng/L,(1.83?0.62)ng/L,(720?167)?g/L;The contents of IL-4,sCD23 and sIL-2R in B group were (84?40)ng/L,(1.72?0.48)ng/L,(649?146)?g/L;Obviously higher than that in control group(41?25)ng/L,(1.10?0.22)ng/L,(367?123)?g/L.The contents of IL-4,sIL-2R and sCD23 after treatment were(60?30)ng/L,(1.11?0.38)ng/L,(540?151)?g/L obviously lower than that before treatment;The contents of IFN-? after treatment were (410?241)?g/L obviously higher than that before treatment (311?240)?g/L;The asthma improved in A group with the 60% of a year increasing 80% of 2 years.Conclusion ESS has a favorable effect on asthma in patients with symptomatic chronic sinusitis.
