Recent advances in study of endothelium-dependent hyperpolarizing factor
- VernacularTitle:血管内皮依赖性超极化因子的研究进展
- Author:
Yifei FAN
;
Dehu KONG
;
Zhiwu CHEN
;
Shan GAO
- Publication Type:Journal Article
- Keywords:
endothelium-dependent hyperpolarization factor;
vasodilatation;
potassium channels
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2004;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Besides cyclooxygenase and nitric oxide synthase, another distinct endothelial pathway, endothelium-dependent hyperpolarization factor (EDHF), is involved in relaxation of the vascular smooth muscle cells. EDHF has been demonstrated unequivocally in various blood vessels from different species, including human, and is likely to play an important role in cardiovascular physiology and pharmacology.
