Genetic advances in hydatidiform mole
- VernacularTitle:葡萄胎遗传学研究进展
- Author:
Jing WANG
;
Shuying WU
;
Xiaowei ZHANG
- Publication Type:Journal Article
- Keywords:
Hydatidiform mole;
Cytogenetics;
Molecular biology
- From:
Journal of Peking University(Health Sciences)
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Hydatidiform mole is the most common gestational trophoblastic disease and is characterized by gross trophoblastic hyperplasia resulting from abnormal fertilization of the oocyte. It is of great interest to researchers because of its propensity for local in vasion and spreading. Using cytogenetic and moleculargenetic techniques researchers have performed various studies on hydatidiform mole. There are advances in the understanding of karyotype, DNA ploidy, fertilization types, expression of imprinted genes, thedifferences between genetic classification and pathologic classification, and the correlation to its invasion and spreading.
