Molecular scanning for MODY5 mutation in Beijing population of familial early-onset type 2 diabetes
- VernacularTitle:北京地区早发糖尿病家系MODY5基因突变的筛查
- Author:
Hetang JIA
- Publication Type:Journal Article
- Keywords:
type 2 diabetes;
MODY;
genetics
- From:Journal of Third Military Medical University
2003;0(19):-
- CountryChina
- Language:Chinese
-
Abstract:
T,1 mutation in coding region including A513T. No target gene mutations were found in 100 controls.Conclusion No enough evidence demonstrates that the variation in or near MODY5 genes is the major cause of early-onset type 2 diabetes in Beijing population.A novel mutation of MODY5 gene was found to possibly relate to diabetes,which mechanism needs to be proved by further study of protein function.
