Preventive effect of bionic pulsed electromagnetic fields on bone mineral density
- VernacularTitle:仿生脉冲电磁场预防性治疗对大鼠继发性骨质疏松骨密度的影响
- Author:
Qing YE
;
Zujian TAN
;
Xianming XIE
;
Junfu CHEN
- Publication Type:Journal Article
- Keywords:
bionic pulsed electromagnetic fields;
bone mineral density;
preventive therapy
- From:Journal of Third Military Medical University
2003;0(19):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the short-term and long-term effect of preventive therapy of bionic pulsed electromagnetic fields(BEMF) on the osteoporosis model of Wistar rats.Methods Thirty-two 3-month-old female Wistar rats were randomly divided into 4 groups with 8 rats in each group: control group(group A),desamethasone group(group B),calcitonin group(group C) and BEMF group(group D).Rats in group A were raised normally and received normal saline.Rats in group B were injected with desamethasone only(1 mg/kg,intramuscularly,twice a week).Rats in group C were injected with calcitonin(2 IU/kg,subcutaneously,once a day) and rats in group D were irradiated with BEMF for preventive therapy,simultaneouly all rats were injected with desamethasone(1 mg/kg,intramuscularly,twice a week).The rat bone mineral density(BMD) was measured under narcosis at 4,8,12 weeks after starting preventive therapy.Results No significant differences in BMD were found among all groups 4 weeks later.The significant differences in BMD were observed between group D and group B 8 weeks later and lasted to 12 weeks(P
