Relationship between augmentation index and severity of coronary artery disease
- VernacularTitle:增强指数与冠心病严重程度的相关性研究
- Author:
Chaoxiang ZHANG
;
Wei CUI
;
Baohua LI
- Publication Type:Journal Article
- Keywords:
Artery stiffness;
Augmentation index;
Coronary heart disease;
Coronary angiography
- From:
Chinese Journal of Practical Internal Medicine
2006;0(19):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore whether augmentation index is an independent risk factor for coronary heart disease or not,and the relationship between augmentation index and coronary artery disease severity.Methods In the study,245 subjects who were hospitalized between Dec.2003 and Dec.2004,were classified into 4 groups and their clinical and biological characteristics and the summary of the scores in each of the eight segment and aortic pressure waveform in ascending aorta were recorded respectively.Results The larger the augmentation index was,the more the number of coronary stenosis vessels was.Linear regression analysis indicated that augmentation index was significantly correlated with grade of coronary stenosis.When augmentation index was more than 45%,the sensibility and specificity was 91.5%and 92.6%respectively.In the logistic regression model,augmentation index was the independent risk factor for coronary heart disease,and the odds ratio of coronary heart disease was 1.893.The 95%CI was 1.421~2.521.Conclusion Augmentation index is an independent risk factor for coronary heart disease and a predictor of angiographic coronary artery disease severity.
