Research on Inhibition of Cell Apoptosis and Multidrug Resistance (MDR)
- VernacularTitle:细胞凋亡抑制与肿瘤多药耐药的研究进展
- Author:
Xingde WO
;
Zhou HOMG
- Publication Type:Journal Article
- Keywords:
genes factors;
apoptosis inhibition;
MDR
- From:
Journal of Zhejiang Chinese Medical University
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
The inhibition of cell apoptosis could result in NDR,because almost all antitumor durgs are inductor of cell apoptosis. According to the study,the overexpression of mutant p53,Bcl-2 family,c-myc gene,NF-kB,HSPs,or ceramide are important reasons in MDR.