Changes of T lymphocyte subgroups in cancer patients and its relationship with tumor staging
- VernacularTitle:恶性肿瘤患者T细胞亚群变化及其与肿瘤分期的关系
- Author:
Xiuhong REN
;
Li LIU
;
Pingping LIU
;
Wenchuan DONG
- Publication Type:Journal Article
- Keywords:
malignant tumor,T-cell subsets,NK cell,flow cytometry
- From:Journal of Third Military Medical University
2003;0(18):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze cellular immunological function of cancer patients in order to provide an evidence for immunological treatment to malignant tumors.Methods T lymphocyte subgroups(total T lymphocytes,Th,Ts,Th/Ts and NK)were determined by flow cytometry in 54 patients with lung cancer,42 with gynecologic cancer,44 with gastrointestinal cancer and 30 healthy individuals.Statistical data were analyzed by SPSS.Results T helper lymphocytes covered(29.41?9.24)%,(34.62?10.27)%,and(32.48?11.64)% respectively in lung,gynecologic and gastrointestinal cancer,significantly lower than that of health people(P
