Acute Toxicity Test of Baicalin Capsule in Mice.
- VernacularTitle:黄芩苷胶囊小鼠急性毒性试验
- Author:
Xiping ZHANG
;
Qihui CHENG
;
Yu ZHANG
- Publication Type:Journal Article
- Keywords:
Baicalin;
Acute toxicity;
Intragastric administration;
Mice
- From:
Journal of Medical Research
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the acute toxic reaction and death of mice one day after intragastric administration of Baicalin capsule so as to appraise its safety. Methods The ICR mice were intragastrically administered with Baicalin powder in capsule at maximum concentration. There was no death of mice found and no LD_ 50 detected after administration. Hence the maximum dosage was identified. Results The maximum dosage of Baicalin powder is 15g/kg. Conclusions The Baicalin capsule is relatively safe.
