Relativity Experimental Study between the Anoxic Blood Vessel Constriction and Endothelium Dependent NO Deficiency.
- VernacularTitle:缺氧性血管收缩与内皮依赖性NO缺陷相关性实验研究
- Author:
Yongbo SUN
;
Aoli SUN
;
Jianbo ZHOU
- Publication Type:Journal Article
- Keywords:
Full endothelium and removed endothelium aorta rings;
NO;
Hypoxia;
Anoxic blood vessel constraction
- From:
Journal of Medical Research
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe effect of large blood vessel hypoxia on the Wister rat′s NO activity. Methods Thoracic aorta rings model with full endothelium and removed endothelium of Wistar rat were prepared , hypoxia stimulated aorta rings and noted changes of constriction extent. Results Endothelium full , removed endothelium aorta rings by hypoxia contract extent difference was 598?42mg and 208?38mg, both had significance discrepancy (P0.05), and NTG made blood vessel contract to reduce range, reach 57.21% (P
