Expression and significance of PCNA,VEGF and MVD in esophageal squamous cell carcinoma
- VernacularTitle:增殖细胞核抗原、血管内皮生长因子和微血管密度在食管鳞癌中的表达及意义
- Author:
Yufei MAO
;
Xiaoyang WANG
;
Hongyan XUE
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Proliferating cell nuclear antigen;
Vascular endothelial growth factors;
Microvessel density
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of proliferating cell nuclear antigen(PCNA),vascular endothelial growth factor(VEGF) and microvessel density(MVD) in squamous cell carcinoma;and to explore the relationship between their expression and tumor biological behavior.Methods The expressions of PCNA,VEGF and MVD were analyzed by immunohistochemical method in 71 cases of esophageal squamous cell carcinoma.Results The intensity positive rate of PCNA indicated close relationship between cell differentiation and lymph node metastasis(P
