Changes of adhesion,aggregation and factor Ⅲ activity of platelet apheresis concentrates in vitro after long-term cryo-preservation at-80 ℃
- VernacularTitle:机采浓缩血小板-80℃长期冻存的动态的体外黏附、聚集功能和Ⅲ因子活性变化
- Author:
Lingkui KONG
;
Weigang ZHU
;
Wen XIONG
;
Xueme LI
- Publication Type:Journal Article
- Keywords:
apheresis platelet concentrates;
liquid platelet;
cry-oplatelet;
cryopreservation;
adhesion;
aggregation;
DMSO
- From:Journal of Third Military Medical University
2003;0(17):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).However,during the thawing process of the APCs,four out of ten and three out of eleven APCs samples appeared aggregative reaction after cryo-preservance for 4 and 5 years,respectively.The majority of the samples extensively lost their factor Ⅲ activities in the fifth year storage.When fresh,liquid platelets were stored at room temperature(22 ℃),the in vitro adhesion and agglutination gradually decreased and statistic differences were observed in 72 h(P