Recent Progress in Research on Reentry of Neurons into the Cell Cycle
- VernacularTitle:神经元细胞周期再进入的研究进展
- Author:
Ping WANG
;
Wei WANG
- Publication Type:Journal Article
- Keywords:
neuron;
cell cycle;
apoptosis;
DNA damage
- From:
International Journal of Cerebrovascular Diseases
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
It has been considered that neurons were in a state of terminal differentiation after postmitosis. Recently, however, many data have suggested that the mature neurons may reentry into the cell cycle. Nevertheless, the mechanism of neuronal cell cycle activation remains unclear. The mechanism of cell cycle is an important part in coping with DNA damage in neurons, and the reentry into the cell cycle is to repair the DNA damage. When the damage is too severe to be repaired, it may induce apoptosis.
