Study of the serum level of soluble E-selectin and its clinical implication in colorectal carcinoma
- VernacularTitle:结直肠癌患者血清可溶性E选择素的检测及其临床意义
- Author:
Hongfeng QI
;
Shiyong LI
;
Ping AN
- Publication Type:Journal Article
- Keywords:
E-selectin;
tumor markers, biological;
colorectal neoplasms
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical significance of the serum level of soluble E-selectin (sE-selectin) in diagnosis and treatment of colorectal cancer. Methods The serum level of sE-selectin was measured by ELISA in 84 patients with colorectal cancer and 30 normal individuals as control. The changes in serum sE-selectin level of 54 patients with colorectal cancer were analyzed preoperatively and postoperatively, and the positive ratio of sE-selectin was compared with that of CEA, CA199 and CA242 in patients with colorectal cancer. Results The serum sE-selectin level in colorectal cancer was significantly higher than that of normal control (P0.05). There was statistically significant difference between the patients with and without hematogenous metastasis (P
