Comparison of some humoral immune indices of hypersplenism treated by radiofrequence ablation or splenectomy
- VernacularTitle:射频消融治疗脾功能亢进症时机体部分体液免疫指标的变化
- Author:
Kai FENG
;
Kuansheng MA
;
Jiahong DONG
- Publication Type:Journal Article
- Keywords:
hypersplenism;
radiofrequency ablation;
humoral immunity;
splenectomy
- From:Journal of Third Military Medical University
2003;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the changes of some humoral immune indices of patients with hypersplenism treated by radiofrequency ablation (RFA). Methods Totally 33 patients met inclusion criteria were randomly assigned to receive RFA (17 patients) as trial group and splenectomy (16 patients) as control group. The level of serum immune globulin,complement and tumor necrosis factor (TNF) in venous blood was determined preoperatively and postoperative 1 week,1 month,and 6 months. We evaluated intergroup differences in immune function by comparing the indices. Results In the trial group,no significant differences were found in humoral immune indices between postoperative and preoperative values. Although the level of postoperative serum complement did not change significantly,serum IgM was lowered significantly (P0.05). Conclusion Because part of the spleen is remained in RFA,the humoral immune function is reserved better than that of splenectomy.
