Effect of Lipide on Mice Podocyte Proliferation
- VernacularTitle:脂质对小鼠肾足细胞增生影响
- Author:
Hongyu CHEN
;
Zhicheng QIN
;
Yongjun WANG
- Publication Type:Journal Article
- Keywords:
Cell Culture;
Mice Podocyte;
LDL;
OX-LDL;
Proliferation
- From:
Journal of Medical Research
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of lipide on mice podcyte prolixferation in vitro culture.Methods MTT was used to dectect the change of the Podocyte Proliferation after the inducement of low-density-liportein(LDL)and oxide-LDL(OX-LDL).Results After 24 and 48 hours,the mice podocyte proliferation increased with the inducement of LDL,which the thickness from 6.25?g/ml to25?g/ml.And after 24 hours,the podocyte proliferation increased with the OX-LDL,which the thickness from 12.5?g/ml to 100?g/ml(compared with control,P
